2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe
Poloxime
CAS: 17302-61-3
Molecular Formula: C10H13NO2
2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe - Names and Identifiers
2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe - Physico-chemical Properties
| Molecular Formula | C10H13NO2 |
| Molar Mass | 179.22 |
| Melting Point | 162℃ (Decomposition) |
| Storage Condition | -20℃ |
| In vitro study | Poloxime (100 μM) inhibits phosphopeptide binding to polo-box domain (PBD) of polo-like kinase 1 (Plk1). |
2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 5.58 ml | 27.899 ml | 55.797 ml |
| 5 mM | 1.116 ml | 5.58 ml | 11.159 ml |
| 10 mM | 0.558 ml | 2.79 ml | 5.58 ml |
| 5 mM | 0.112 ml | 0.558 ml | 1.116 ml |
Last Update：2024-01-02 23:10:35
2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe - Reference Information
| biological activity | Poloxime is a hydrolysis product of poloxin, which is a non-competitive Plk1 inhibitor of ATP, the activity of Plk1 can be suitably inhibited. |
Last Update：2024-04-09 02:00:14
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CAS: 17302-61-3
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CAS: 17302-61-3
Tel: 18301782025
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